Deux traitements sont actuellement étudiés pour lutter contre les formes graves du Covid-19

Multiple sclerosis: a virus of origin?

Two treatments are currently being studied to combat severe forms of Covid-19
The discovery of the link between the Epstein-Barr virus and multiple sclerosis could make it possible to combat the disease more effectively. (© Adobe Stock illustration)

in France, 130,000 people 80% of young women are affected by the autoimmune disease multiple sclerosis, according to the French Society of Multiple Sclerosis (AFSEP).

And the number of patients continues to grow: “Every year, there are 2000 new diagnoses who falls,” warns Jocelyn Novett-Gere, president of AFSEP, who contacted her Actu.

But that number may drop soon, with a vaccine likely.

Virus that causes multiple sclerosis

Scientists at Harvard University have discovered that multiple sclerosis is more likely Related to the Epstein-Barr virus (EBV), which also causes other diseases, such as mononucleosis.

They present their findings in a study titled Longitudinal analysis reveals a high prevalence of the Epstein-Barr virus associated with multiple sclerosis, in English, in the journal Science.

To come to this conclusion, the scientists had access to data from 10 million US Army soldiers, spanning from 1993 to 2013.

In a sample of 801 soldiers infected with the disease Only one was negative for EBV, the scientists explained.

This finding provides compelling data indicating that the Epstein-Barr virus causes multiple sclerosis

William H. Robinson and Lawrence Steinmanin suspension of study

However, the discovery is still in its infancy: “EBV infection appears to be necessary, but not sufficient to trigger disease,” commented Williams H.

In other words, other forces certainly play a role during the development of multiple sclerosis.

Towards a vaccine and treatments?

But this scientific advance could lead to an improvement in the fight against multiple sclerosis. Moderna announced on January 5, 2022 that it is working on an RNA vaccine.

This one is only in the testing phase at the moment, and should not see the light of day for a while. However, theClinical trial just launched.

“Phase I will be implemented at about 15 sites in the United States. The main goal is to assess the tolerance of the vaccine in healthy adults aged 18 to 30 years,” Moderna said in its press release.

However, the study authors remain very ambiguous regarding a potential treatment: “Will antivirals that target EBV provide an effective treatment? This is a possibility, given that targeting EBV appears to have many advantages over current therapies.”

As Williams H. said: Robinson and Lawrence Steinman, “Now that the trigger has been discovered, multiple sclerosis may be eradicated.”

What is multiple sclerosis?

It is a disease that attacks the central nervous system. It usually gets worse slowly and is said to be in a “flare up” state. New symptoms appear one after another. Speak first on the scheduled date so that you sometimes settle down for the long haul.
Within our bodies, we have many neural connections, allowing information to be transmitted from the brain to the rest of the system.
These connections are protected by sheaths called myelin. They are ill. Thus the immune system begins to regard them as aliens and destroys them. (This is the principle of the autoimmune reaction).
Jocelyn Novet-Gere, president of the French Society of Multiple Sclerosis (AFSEP), who suffers from the disease compares it to a car engine that will disconnect its wires one by one. “Obviously this creates problems.”
This disease causes many problems for those who carry it due to the multiplicity of symptoms. “You can lose your visual acuity, you lose your mobility, your libido, you are tired all the time, and thus you lose social connections. This also makes family life complicated…,” the AFSEP president recounts.
Although multiple sclerosis is not hereditary, scientists have discovered that certain genes, passed on by our parents, can thus increase susceptibility to the disease.

“Nothing has been done yet”

I fear this ad will have a terrible effect. Many members contact us and think they will be cured. That’s not on the agenda right now,” Jocelyn Novet-Gere laments. “Nothing has been done yet,” she recalls.

“Despite being shortened by scientific progress, an accurate diagnosis of multiple sclerosis takes time. Also, I’m afraid those who have doubts will shrug it off by saying to themselves ‘That’s fine, we have something to fight for.’ No, listen to your doubts and make all your claims. Necessary checks,” warns the AFSEP chief.

At the moment, there is no way to prevent pathology. The only treatments that exist consist of “keeping the acute attacks apart,” Jocelyn Novet-Gere explains.

Therefore, this progression can be, if decisive, a great hope In the fight against multiple sclerosis.

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